STEM与日常科技·英语30篇(3)
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Single-Cell Sequencing Reveals Cellular Heterogeneity
单细胞测序揭示细胞异质性
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Even within one organ, no two human cells are genetically or functionally identical—single-cell sequencing proves this.
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Scientists isolate individual cells first, then read their full RNA profiles instead of averaging across thousands.
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This method uncovered rare immune cells that trigger severe asthma attacks but stay invisible in bulk tests.
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Tumors once thought uniform now show distinct subpopulations—one resistant to chemo, another prone to spread.
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Doctors use these maps to design therapies targeting only dangerous cell types, sparing healthy ones.
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In aging brains, the technique revealed why some neurons decline early while neighbors remain active for decades.
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It also explains why identical twins may develop different diseases despite near-identical DNA.
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By treating each cell as a unique data point, biologists move beyond population averages to true biological nuance.