STEM与日常科技·英语30篇（3）
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Single-Cell Sequencing Reveals Cellular Heterogeneity
单细胞测序揭示细胞异质性
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Even within one organ, no two human cells are genetically or functionally identical—single-cell sequencing proves this.即使在同一器官内，也没有任意两个人体细胞在基因或功能上完全相同——单细胞测序证实了这一点。
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Scientists isolate individual cells first, then read their full RNA profiles instead of averaging across thousands.科学家首先分离单个细胞，再完整读取其RNA谱，而非对成千上万个细胞取平均值。
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This method uncovered rare immune cells that trigger severe asthma attacks but stay invisible in bulk tests.该方法发现了引发重度哮喘发作的稀有免疫细胞，而这些细胞在常规批量检测中无法被察觉。
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Tumors once thought uniform now show distinct subpopulations—one resistant to chemo, another prone to spread.过去被认为均质的肿瘤，如今显示出截然不同的亚群：一类耐化疗，另一类易转移。
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Doctors use these maps to design therapies targeting only dangerous cell types, sparing healthy ones.医生利用这些细胞图谱设计靶向疗法，精准清除危险细胞类型，同时保护健康细胞。
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In aging brains, the technique revealed why some neurons decline early while neighbors remain active for decades.在衰老大脑中，该技术揭示了为何某些神经元早早衰退，而邻近神经元却能持续活跃数十年。
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It also explains why identical twins may develop different diseases despite near-identical DNA.它也解释了为何同卵双胞胎尽管DNA几乎完全相同，却可能患上不同疾病。
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By treating each cell as a unique data point, biologists move beyond population averages to true biological nuance.通过将每个细胞视为独立数据点，生物学家得以超越群体平均值，深入把握真实的生物学细微差异。