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Homomorphic Encryption in Healthcare Portals: Practical Limits of Computation on Encrypted Patient Records

Homomorphic Encryption in Healthcare Portals: Practical Limits of Computation on Encrypted Patient Records

医疗门户中的同态加密:对加密患者记录执行计算的实际边界

  1. Healthcare portals increasingly advertise homomorphic encryption as enabling secure analytics without decrypting sensitive medical histories.
  2. Yet fully homomorphic schemes remain computationally prohibitive for real-time queries on multi-gigabyte EHR datasets.
  3. Most deployed systems use leveled variants—supporting only fixed-depth operations before noise accumulation invalidates results.
  4. A clinician searching for diabetic patients with specific lab trends may trigger decryption fallbacks without clear user notification.
  5. Cloud providers offering HE-as-a-service charge premiums that scale exponentially with circuit complexity and ciphertext size.
  6. Interoperability suffers because encrypted fields cannot participate in standard FHIR resource matching or indexing protocols.
  7. Patients assume end-to-end encryption guarantees confidentiality, overlooking that computation itself leaks metadata about query intent and volume.
  8. Regulatory audits focus on key management and access logs—not whether homomorphic operations introduce side-channel leakage during evaluation.
  9. Practical adoption hinges on hybrid architectures: encrypting identifiers while leaving non-sensitive metadata searchable in plaintext.
  10. HE excels for narrow, pre-approved computations—like aggregating anonymized treatment outcomes—not open-ended clinical exploration.
  11. Engineers must communicate trade-offs transparently: latency increases by 100–500x, and result precision degrades with operation depth.
  12. True security requires understanding where HE ends—and where human-reviewed policy, audit trails, and access governance must begin.

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