How Epigenetic Modifications Mediate Transgenerational Responses to Environmental Stress

表观遗传修饰如何介导环境压力的跨代响应？

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Environmental stressors—including famine, toxins, and psychosocial trauma—induce DNA methylation and histone modifications that alter gene expression without changing nucleotide sequences.
These marks can escape epigenetic reprogramming during gametogenesis and early embryogenesis, transmitting phenotypic effects to offspring.

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